Genomic Insights for Better Lung Disease Understanding

Last updated: March 2026

The Woodruff Laboratory shares selected genomic summary outputs from airway and lung studies to support transparency, reuse, and collaboration. These files are intended for research and educational use and include curated differential expression (DE) results and plot sets.

How to use these files

  • DE tables provide ranked gene lists (e.g., top genes by differential expression) with effect sizes and significance values.
  • Plot sets provide visual summaries for comparisons, as described below.
  • If you use these resources in a manuscript or presentation, please cite the corresponding dataset accession and relevant Woodruff Lab publications.

Basic genomic analyses

Differential gene expression analysis (Affymetrix U133 Plus 2.0 arrays).

Healthy vs steroid-naive asthma

Epithelial brushing

27 healthy controls vs 41 steroid-naive asthmatics (with 31 paired post-steroid samples).
Download: DE table (Top 1,000 genes)
Related dataset: GSE4302 (GEO)

Biopsy homogenates

15 healthy controls vs 32 steroid-naive asthmatics (with 31 paired post-steroid samples).
Download: DE table (Top 1,000 genes)
Related dataset: GSE23611 (GEO)

Alveolar macrophages

15 healthy controls vs 17 steroid-naive asthmatics.
Download: DE table (Top 1,000 genes)
Related dataset: GSE2125 (GEO)


Healthy vs Smoker

Downloadable plot set for the comparison of 15 Healthy vs 15 Smoker.


microRNA differential expression analysis (ADMIRE)

microRNA differential expression analysis (ADMIRE) (data assayed on custom Agilent arrays).

Click here to download the plots: Top 217 DE miRNAs .


Questions or requests

For questions about these files, access requests, or collaboration inquiries, please use the Contact Us page.