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Su R, Li MM, Bhakta NR, Solberg OD, Darnell EP, Ramstein J, Garudadri S, Ho M, Woodruff PG, Koth LL. Longitudinal analysis of sarcoidosis blood transcriptomic signatures and disease outcomes. Eur Respir J. 2014 Aug 19. PMID: 25142485
Greer AM, Wu N, Putnam AL, Woodruff PG, Wolters P, Kinet JP, Shin JS. Serum IgE clearance is facilitated by human FcεRI internalization. J Clin Invest. 2014 Mar 3;124(3):1187-98. PubMed PMID: 24569373; PubMed Central PMCID: PMC3938266.
O'Neal WK, Anderson W, Basta PV, Carretta EE, Doerschuk CM, Barr RG, Bleecker ER, Christenson SA, Curtis JL, Han MK, Hansel NN, Kanner RE, Kleerup EC, Martinez FJ, Miller BE, Peters SP, Rennard SI, Scholand MB, Tal-Singer R, Woodruff PG, Couper DJ, Davis SM; reporting for SPIROMICS Investigators. Comparison of serum, EDTA plasma and P100 plasma for luminex-based biomarker multiplex assays in patients with chronic obstructive pulmonary disease in the SPIROMICS study. J Transl Med. 2014 Jan 8;12(1):9. PubMed PMID: 24397870; PubMed Central PMCID: PMC3928911
Roy MG, Livraghi-Butrico A, Fletcher AA, McElwee MM, Evans SE, Boerner RM, Alexander SN, Bellinghausen LK, Song AS, Petrova YM, Tuvim MJ, Adachi R, Romo I, Bordt AS, Bowden MG, Sisson JH, Woodruff PG, Thornton DJ, Rousseau K, De la Garza MM, Moghaddam SJ, Karmouty-Quintana H, Blackburn MR, Drouin SM, Davis CW, Terrell KA, Grubb BR, O'Neal WK, Flores SC, Cota-Gomez A, Lozupone CA, Donnelly JM, Watson AM, Hennessy CE, Keith RC, Yang IV, Barthel L, Henson PM, Janssen WJ, Schwartz DA, Boucher RC, Dickey BF, Evans CM. Muc5b is required for airway defence. Nature. 2014 Jan 16;505(7483):412-6. PubMed PMID: 24317696
Woodruff PG, Chatila W, Connett JE, Criner GJ, Curtis JL, Dransfield MT, Han MK, Lazarus SC, Marchetti N, Rogers TJ, Scanlon PD, Sin DD, Voelker H, Wendt C, Albert RK; for the COPD Clinical Research Network. Tumour necrosis factor receptor 75 and risk for COPD exacerbation in the azithromycin trial. Eur Respir J. 2014 Jan;43(1):295-8. PubMed PMID: 24136332
Woodruff PG. Subtypes of asthma defined by epithelial cell expression of messenger RNA and microRNA. Ann Am Thorac Soc. 2013 Dec;10 Suppl:S186-9. PubMed PMID: 24313771
Su R, Nguyen ML, Agarwal MR, Kirby C, Nguyen CP, Ramstein J, Darnell EP, Gomez AD, Ho M, Woodruff PG, Koth LL. Interferon-inducible chemokines reflect severity and progression in sarcoidosis. Respir Res. 2013 Nov 7;14(1):121. PubMed PMID: 24199653.
Peters MC, Mekonnen ZK, Yuan S, Bhakta NR, Woodruff PG, Fahy JV. Measures of gene expression in sputum cells can identify T(H)2-high and T(H)2-low subtypes of asthma. J Allergy Clin Immunol. 2013 Sep 24. doi:pii: S0091-6749(13)01209-8. PubMed PMID: 24075231
Couper D, Lavange LM, Han M, Barr RG, Bleecker E, Hoffman EA, Kanner R, Kleerup E, Martinez FJ, Woodruff PG, Rennard S; for the SPIROMICS Research Group. Design of the Subpopulations and Intermediate Outcomes in COPD Study (SPIROMICS). Thorax. 2013 Sep 12. doi: 10.1136/thoraxjnl-2013 203897. [Epub ahead of print] PubMed PMID: 24029743
Bhakta NR, Solberg OD, Nguyen CP, Nguyen CN, Arron JR, Fahy JV, Woodruff PG. A qPCR-based metric of Th2 airway inflammation in asthma. Clin Transl Allergy. 2013 Jul 17;3(1):24. doi: 10.1186/2045-7022-3-24. PubMed PMID: 23866775; PubMed Central PMCID: PMC3724712
Hallstrand TS, Lai Y, Altemeier WA, Appel CL, Johnson B, Frevert CW, Hudkins KL, Bollinger JG, Woodruff PG, Hyde DM, Henderson WR Jr, Gelb MH. Regulation and function of epithelial secreted phospholipase A2 group x in asthma. Am J Respir Crit Care Med. 2013 Jul 1;188(1):42-50. doi: 10.1164/rccm.201301-0084OC. PubMed PMID: 23614662
Mooney JJ, Elicker BM, Urbania TH, Agarwal MR, Ryerson CJ, Nguyen ML, Woodruff PG, Jones KD, Collard HR, King TE, Koth LL. Radiographic Fibrosis Score Predicts Survival in Hypersensitivity Pneumonitis. Chest. 2013 Feb 7. doi: 10.1378/chest.12-2623
Levänen B, Bhakta NR, Torregrosa Paredes P, Barbeau R, Hiltbrunner S, Pollack JL, Sköld CM, Svartengren M, Grunewald J, Gabrielsson S, Eklund A, Larsson BM, Woodruff PG, Erle DJ, Wheelock AM. Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients. J Allergy Clin Immunol. 2013 Mar;131(3):894-903.
Seumois G, Vijayanand P, Eisley CJ, Omran N, Kalinke L, North M, Ganesan AP, Simpson LJ, Hunkapiller N, Moltzahn F, Woodruff PG, Fahy JV, Erle DJ, Djukanovic R, Blelloch R, Ansel KM. An integrated nano-scale approach to profile miRNAs in limited clinical samples. Am J Clin Exp Immunol. 2012 Nov 30;1(2):70-89.
Kudo M, Khalifeh Soltani SM, Sakuma SA, McKleroy W, Lee TH, Woodruff PG, Lee JW, Huang K, Chen C, Arjomandi M, Huang X, Atabai K. Mfge8 suppresses airway hyperresponsiveness in asthma by regulating smooth muscle contraction. Proc Natl Acad Sci U S A. 2013 Jan 8;110(2):660-5.
Albert RK, Connett J, Curtis JL, Martinez FJ, Han MK, Lazarus SC, Woodruff PG. Mannose-binding lectin deficiency and acute exacerbations of chronic obstructive pulmonary disease. Int J Chron Obstruct Pulmon Dis. 2012;7:767-77.
Huang F, Zhang H, Wu M, Yang H, Kudo M, Peters CJ, Woodruff PG, Solberg OD, Donne ML, Huang X, Sheppard D, Fahy JV, Wolters PJ, Hogan BL, Finkbeiner WE, Li M, Jan YN, Jan LY, Rock JR. Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction. Proc Natl Acad Sci U S A. 2012 Sep 17.
Solberg OD, Ostrin EJ, Love MI, Peng JC, Bhakta NR, Hou L, Nguyen C, Solon M, Nguyen C, Barczak AJ, Zlock LT, Blagev DP, Finkbeiner WE, Ansel KM, Arron JR, Erle DJ, Woodruff PG. Airway Epithelial miRNA Expression is Altered in Asthma. Am J Respir Crit Care Med. 2012 Sep 6.
Jia G, Erickson RW, Choy DF, Mosesova S, Wu LC, Solberg OD, Shikotra A, Carter R, Audusseau S, Hamid Q, Bradding P, Fahy JV,Woodruff PG, Harris JM, Arron JR; Bronchoscopic Exploratory Research Study of Biomarkers in Corticosteroid-refractory Asthma (BOBCAT) Study Group. Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients. J Allergy Clin Immunol. 2012 Aug 1.
Diez D, Goto S, Fahy JV, Erle DJ, Woodruff PG, Wheelock AM, Wheelock CE. Network analysis identifies a putative role for the PPAR and type 1 interferon pathways in glucocorticoid actions in asthmatics. BMC Med Genomics. 2012 Jun 19;5:27.
Dransfield MT, Harnden S, Burton RL, Albert RK, Bailey WC, Casaburi R, Connett J, Cooper JA, Criner GJ, Curtis JL, Han MK, Make B, Marchetti N, Martinez FJ, McEvoy C, Nahm MH, Niewoehner DE, Porszasz J, Reilly J, Scanlon PD, Scharf SM, Sciurba FC, Washko GR, Woodruff PG, Lazarus SC; for the NIH COPD Clinical Research Network. Long-term Comparative Immunogenicity of Protein Conjugate and Free Polysaccharide Pneumococcal Vaccines in Chronic Obstructive Pulmonary Disease. Clin Infect Dis. 2012 Sep;55(5):e35-e44. Epub 2012 May 31.
A Combined Pulmonary-Radiology Workshop for Visual Evaluation of COPD: Study Design, Chest CT Findings and Concordance with Quantitative Evaluation. Barr CC, Berkowitz EA, Bigazzi F, Bode F, Bon J, Bowler RP, Chiles C, Crapo JD, Criner GJ, Curtis JL, Dass C, Dirksen A, Dransfield MT, Edula G, Erikkson L, Friedlander A, Galperin-Aizenberg M, Gefter WB, Gierada DS, Grenier PA, Goldin J, Han MK, Hanania NA, Hansel NN, Jacobson FL, Kauczor HU, Kinnula VL, Lipson DA, Lynch DA, Macnee W, Make BJ, Mamary AJ, Mann H, Marchetti N, Mascalchi M, McLennan G, Murphy JR, Naidich D, Nath H, Newell JD Jr, Pistolesi M, Regan EA, Reilly JJ, Sandhaus R, Schroeder JD, Sciurba F, Shaker S, Sharafkhaneh A, Silverman EK, Steiner RM, Strange C, Sverzellati N, Tashjian JH, Beek EJ, Washington L, Washko GR, Westney G, Wood SA, Woodruff PG. COPD. 2012 Apr;9(2):151-159.
Influence of lightweight ambulatory oxygen on oxygen use and activity patterns of COPD patients receiving long-term oxygen therapy. Casaburi R, Porszasz J, Hecht A, Tiep B, Albert RK, Anthonisen NR, Bailey WC, Connett JE, Cooper JA Jr, Criner GJ, Curtis J, Dransfield M, Lazarus SC, Make B, Martinez FJ, McEvoy C, Niewoehner DE, Reilly JJ, Scanlon P, Scharf SM, Sciurba FC,Woodruff P; COPD Clinical Research Network. COPD. 2012 Feb;9(1):3-11.
Vitamin D levels and risk of acute exacerbations of chronic obstructive pulmonary disease: a prospective cohort study. Kunisaki KM, Niewoehner DE, Connett JE; COPD Clinical Research Network. Am J Respir Crit Care Med. 2012 Feb 1;185(3):286-90. Epub 2011 Nov 10
Gordon ED, Sidhu SS, Wang ZE, Woodruff PG, Yuan S, Solon MC, Conway SJ, Huang X, Locksley RM, Fahy JV. A protective role for periostin and TGF-β in IgE-mediated allergy and airway hyper-responsiveness. Clin Exp Allergy. 2012 Jan;42(1):144-55.
Albert RK, Connett J, Bailey WC, Casaburi R, Cooper JAD, Criner GJ, Curtis JL, Dransfield MT, Han MK, Lazarus SC, Make B, Marchetti N, Martinez FJ, Madinger NA, McEvoyC, Niewoehner DE, Porsasz J, Price, CS, Reilly J, Scanlon PD, Sciurba FC, Scharf SM, Washko GR, Woodruff PG, and Anthonisen NR. for the COPD Clinical Research Network. Azithromycin for Prevention of Exacerbations of COPD. N Engl J Med 2011; 365:689-698
Koth LL, Solberg OD, Peng JC, Bhakta NR, Nguyen CP, Woodruff PG. Sarcoidosis Blood Transcriptome Reflects Lung Inflammation and Overlaps with Tuberculosis. Am J Respir Crit Care Med. 2011 Nov 15;184(10):1153-63.
Woodruff PG. Novel Outcomes and End-points: Biomarkers in COPD Clinical Trials. Proc Am Thorac Soc. 2011 Aug;8(4):350-5.
Bhakta N, Woodruff PG. Human Asthma Phenotypes: From the Clinic, to Cytokines, and Back Again Immunol Rev. 2011 Jul;242(1):220-32.
Woodruff PG, Albert RK, Bailey WC, Casaburi R, Connett JE, Cooper JAD, Criner GJ, Curtis JL, Dransfield MT, Han MK, Harnden SM, Kim V, Marchetti N, Martinez FJ, McEvoy CE, Niewoehner DE, Reilly JJ, Rice K, Scanlon PD, Scharf SM, Sciurba FC, Washko GR, Lazarus SC for the COPD Clinical Research Network. Randomized Trial of Zileuton for Treatment of COPD Exacerbations Requiring Hospitalization. COPD. 2011 Feb;8(1):21-9. PMC Journal – In Process
Choy DF, Modrek B, Abbas AR, Kummerfeld S, Clark HF, Wu LC, Fedorowicz G, Modrusan Z, Fahy JV, Woodruff PG, Arron JR. Gene expression patterns of th2 inflammation and intercellular communication in asthmatic airways. J Immunol. 2011 Feb 1;186(3):1861-9. PMC Journal – In Process
Innes AL, McGrath KW, Dougherty RH, McCulloch CE, Woodruff PG, Seibold MA, Okamoto KS, Ingmundson KJ, Solon M, Carrington SD, Fahy JV. The H Antigen at Epithelial Surfaces is Associated with Susceptibility to Asthma Exacerbation. Am J Respir Crit Care Med. 2011 Jan 15;183(2):189-94. PMC Journal – In Process
Sidhu SS, Yuan S, Innes AL, Woodruff PG, Solon M, Hou L, Muller SJ, and Fahy JV.Epithelial cell-derived periostin: roles in TGFbeta activation, collagen production and collagen gel elasticity in asthma. Proc Natl Acad Sci U S A. 2010 [in Press].
Innes AL, McGrath KW, Dougherty RH, McCulloch CE, Woodruff PG, Seibold MA, Okamoto KS, Ingmundson KJ, Solon M, Carrington SD, Fahy JV. The H Antigen at Epithelial Surfaces is Associated with Susceptibility to Asthma Exacerbation. Am J Respir Crit Care Med. 2010 [in Press].
Koth LL, Cambier CJ, Ellwanger A, Solon M, Hou L, Lanier LL, Abram CL, Hamerman JA, Woodruff PG. DAP12 is required for macrophage recruitment to the lung in response to cigarette smoke and chemotaxis toward CCL2. J Immunol. 2010 Jun 1;184(11):6522-8. Epub 2010 Apr 26. PubMed PMID: 20421649.
Dougherty RH, Sidhu SS, Raman K, Solon M, Solberg OD, Caughey GH, Woodruff PG, Fahy JV. Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma. J Allergy Clin Immunol. 2010 May;125(5):1046-1053.e8.
Woodruff PG, Wolff M, Hohlfeld JM, Krug N, Dransfield MT, Sutherland ER, Criner GJ, Kim V, Prasse A, Nivens MC, Tetzlaff K, Heilker R, Fahy JV. Safety and Efficacy of an Inhaled Epidermal Growth Factor Receptor Inhibitor (BIBW 2948 BS) in COPD. Am J Respir Crit Care Med. 2010 Mar 1;181(5):438-45.
Hsia CC, Hyde DM, Ochs M, Weibel ER; ATS/ERS Joint Task Force on Quantitative Assessment of Lung Structure. An official research policy statement of the American Thoracic Society/European Respiratory Society: standards for quantitative assessment of lung structure. Am J Respir Crit Care Med. 2010 Feb 15;181(4):394-418.
Park SW, Verhaeghe C, Nguyenvu LT, Barbeau R, Eisley CJ, Nakagami Y, Huang X, Woodruff PG, Fahy JV, Erle DJ. Roles of FOXA2 and FOXA3 in Allergic Airway Disease and Asthma. Am J Respir Crit Care Med. Jul 23 2009 Oct 1;180(7):603-10. PMCID: PMC2753788
Dransfield MT, Nahm MH, Han MK, Harnden S, Criner GJ, Martinez FJ, Scanlon PD, Woodruff PG, Washko GR, Connett JE, Anthonisen NR, Bailey WC. Superior Immune Response to Protein-conjugate vs. Free Pneumococcal Polysaccharide Vaccine in COPD. Am J Respir Crit Care Med. 2009 Sep 15;180(6):499-505. PMCID: PMC2742743
Woodruff PG, Modrek B, Choy DF, Jia G, Abbas AR, Ellwanger A, Koth LL, Arron JR, and Fahy JV. Th2-driven inflammation defines major sub-phenotypes of asthma. Am J Respir Crit Care Med 2009 Sep 1;180(5):388-95. PMCID: PMC2742757
Goswami S, Angkasekwinaim P, Shan M, Greenlee KJ, Barranco WT, Polikepahad S, Seryshev A, Redding D, Singh B, Sur S,Woodruff PG, Dong C, Corry DB, Kheradmand F. Divergent Roles for Airway Epithelial MMP7 and Retinoic Acid in Experimental Asthma, Nature Immunology, 2009 May;10(5):496-503. PMID: 19329997
Hecht A, Ma S, Porszasz J, Casaburi R; COPD Clinical Research Network. Methodology for using long-term accelerometry monitoring to describe daily activity patterns in COPD. COPD. 2009 Apr;6(2):121-9.
Woodruff PG, Ellwanger A, Solon M, Cambier CJ, Pinkerton KE, Koth LL. Alveolar Macrophage Recruitment and Activation by Chronic Second Hand Smoke Exposure in Mice. COPD 2009 Apr;6(2):86-94. PMID: 19378221
Seibold MA, Donnelly S, Solon M, Innes A, Woodruff PG, Boot RG, Burchard EG,
Fahy JV. Chitotriosidase is the primary active chitinase in the human lung and is modulated by genotype and smoking habit. J Allergy Clin Immunol. 2008 Nov;122(5):944-950. PMCID: PMC2666777
Schane RE, Walter LC, Dinno A, Covinsky KE, Woodruff PG. Prevalence and Risk Factors for Depressive Symptoms in Persons with Chronic Obstructive Pulmonary Disease. J Gen Int Med. 2008 Nov;23(11):1757-62. PMCID: PMC2585678
Panettieri Jr RA, Kotlikoff MI, Gerthoffer WT, Hershenson MB, Woodruff PG, Hall IP, Banks-Schlegel SP. Airway Smooth Muscle in Bronchial Tone, Inflammation and Remodeling: Basic to Clinical Relevance. Am J Respir Crit Care Med. 2008 Feb 1;177(3):248-52. PMCID: PMC2218850
Woodruff PG, Boushey HA, Dolganov GM, Barker CS, Yang YH, Donnelly S, Ellwanger A, Sidhu SS, Dao-Pick TP, Pantoja C, Erle DJ, Yamamoto KR, Fahy JV. Genome-Wide Profiling Identifies Epithelial Cell Genes Associated with Asthma and with Treatment Response to Corticosteroids. Proc Natl Acad Sci U S A. 2007 Oct 2;104(40):15858-63. PMCID: PMC2000427
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